Highlights:

• Amino acid that increases serotonin production.

• Prevents serotonin depletion and protects against neurotoxicity.

• Supports positive mood and reduces anxiety.

• Promotes normal sleep patterns.

Scientific Research Indicates:

5-HTP, the direct precursor to the neurotransmitter serotonin, is the quickest and most effective way to boost and replenish serotonin in the brain.+ Stress, lack of sleep, and exposure to chemical toxins accelerate serotonin depletion which can result in irritability, anxiety, insomnia, and depression. 5-HTP expedites the restoration of normal serotonin levels to promote normal brain function and good mental health.*

+ Birdsall, T.C., 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern Med Rev, 1998. 3(4): p. 271-80. http://www.ncbi.nlm.nih.gov/pubmed/9727088 

Highlights:

• Protects and repairs brain cells.

• Enhances cognitive function.

• Helps maintain a healthy brain and positive mood.

• Promotes exercise recovery.

Scientific Research Indicates:

L-Carnitine has a significant effect on healthy neurological function, working to protect neurons against oxidative damage and enhance brain cell activity. It ensures a positive mood and a heightened memory.* Studies suggest that L-Carnitine decreases the production of free radicals and promotes exercise recovery by moderating tissue damage.+ Fumarate is an important compound that plays a key role in replenishing energy levels. Combined, L-Carnitine and Fumarate provide dual support for maximum recovery, unlike most forms of Carnitine.

+ Glade MJ. Oxidative stress and cognitive longevity. Nutrition. 2010 Jun;26(6):595-603. http://www.ncbi.nlm.nih.gov/pubmed/20083385

+ Huang A, Owen K. Role of supplementary l-carnitine in exercise and exercise recovery. Med Sport Sci. 2012;59:135-42 http://www.ncbi.nlm.nih.gov/pubmed/23075564 

Highlights:

• The “universal antioxidant” and ultimate protection against free radicals.

• Increases blood flow and oxygen to the nerves, improving brain function and memory.

• Detoxifies the liver.

• Recycles key antioxidants including Vitamin C and Vitamin E.

Scientific Research Indicates:

Alpha Lipoic Acid is a fatty acid naturally found inside every cell in the body, where its needed to convert glucose into energy for all normal body functions. Unlike other antioxidants, which work only in water (such as vitamin C) or fatty tissues (such as vitamin E), Alpha Lipoic Acid is known as the “universal antioxidant” because it’s both fat and water soluble, meaning it can work throughout the body. Antioxidants (like vitamin C and E) are depleted as they attack free radicals, but evidence suggests that Alpha Lipoic Acid can recycle and rejuvenate other antioxidants to make them active again.+ Alpha Lipoic Acid protects the body from harm and boosts the healing powers of antioxidants.*

+ Packer L, Tritschler HJ, Wessel K (1997). Neuroprotection by the metabolic antioxidant alpha-lipoic acid. Free radical biology & medicine 22 (1–2): 359–78. http://www.ncbi.nlm.nih.gov/pubmed/8958163 

Highlights:

• An antioxidant necessary for brain activity.

• Increases serotonin production.

• Reduces the risk of neurotoxicity.

• Improves immune function.

Scientific Research Indicates:

Coenzyme Q10 (also known as CoQ10) is a potent antioxidant that can neutralize free radicals and prevent neurotoxicity.+ It protects the brain and the rest of the nervous system from damage and helps combat fatigue.* Coenzyme Q10 improves energy production in cells which ensures healthy brain activity.

+ Somayajulu M, McCarthy S, Hung M, Sikorska M, Borowy-Borowski H, Pandey S. Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10. Neurobiol Dis. 2005 Apr;18(3):618-27. http://www.ncbi.nlm.nih.gov/pubmed/15755687 

Highlights:

• A powerful antioxidant that intercepts and neutralizes free radicals.

• Defends the body against stress and promotes rapid recovery.

• Boosts immune system.

• Recycles Vitamin E.

Scientific Research Indicates:

Vitamin C is a powerful antioxidant and essential nutrient vital for the repair of tissues in all parts of the body. It also plays a very important role in immune function by increasing the production of infection-fighting white blood cells. Vitamin C is highly effective in fighting free radicals, minimizing damage from outside toxins, and promoting rapid recovery.*+

+ Padh H. Vitamin C: newer insights into its biochemical functions. Nutr Rev 1991 Mar;49(3):65-70. http://www.ncbi.nlm.nih.gov/pubmed/2057141 

Highlights:

• An antioxidant that reduces free radical formation.

• Protects brain cells from damage.

• Boosts immune system.

• Supports healthy heart, muscles, and nerves.

Scientific Research Indicates:

Vitamin E is a fat-soluble vitamin, meaning it leaves the body much slower than a water-soluble vitamin and can penetrate deeply into fatty tissues (including the brain). It’s one of the most powerful biologically active antioxidants particularly important for the protection of cell membranes. It supports a strong immune system and is necessary for maintaining the health of the heart, muscles, and nerves.+ Vitamin E prevents brain cell damage, improves physical endurance, and encourages full body restoration.* d-alpha Tocopheryl Succinate is the natural form of Vitamin E which is twice as bioavailable (available for use by the body) as the synthetic form commonly found in other nutritional supplements.

+ Brigelius-Flohé; Traber, MG (1999). Vitamin E: function and metabolism. The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 13 (10): 1145–55. http://www.ncbi.nlm.nih.gov/pubmed/10385606 

Highlights:

• Helps detoxify the body of toxins.

• Promotes rapid recovery.

• Improves circulation and combats fatigue.

• Supports a healthy nervous system.

Scientific Research Indicates:

Vitamin B3 opens up capillaries and blood vessels, allowing the restorative power of oxygenated blood to cleanse and detoxify the system.*+ Stress on the mind and body rapidly causes a retreat of blood to the core of the body. Vitamin B3 helps restore and increase the blood flow throughout the body, speeding up the cleansing of toxins.

+ Am J Cardiol. Mechanism of action of niacin. 2008 Apr 17;101(8A):20B-26B http://www.ncbi.nlm.nih.gov/pubmed/18375237 

Highlights:

• Helps to convert 5-HTP into serotonin, thereby boosting its effect.

• Increases energy and improves mental focus.

• Boosts immune system.

• Increases the bioavailability of Magnesium, making it more easily absorbed.

Scientific Research Indicates:

Vitamin B6 performs a wide variety of functions in the body including maintaining a healthy immune system and assisting in the formation of important neurotransmitters (including serotonin). Scientific studies show that 5-HTP is much more effective at producing serotonin in the brain when taken with vitamin B6.+  Vitamin B6 deficiency can be quite common because alcohol, caffeine, smoking, and physical exercise increase the excretion of vitamin B6 in the urine. Vitamin B6 ensures the conversion of 5-HTP into serotonin, releases natural energy, and is vital for defending against stress.*

+ Hartvig P, Lindner KJ, Bjurling P, Langstrom B, Tedroff J. Pyridoxine effect on synthesis rate of serotonin in the monkey brain measured with positron emission tomography. J Neural Trans 1995;102:91-97. http://www.ncbi.nlm.nih.gov/pubmed/8748674

+ Dakshinamurti K, Sharma SK, Bonke D. Influence of B vitamins on binding properties of serotonin receptors in the CNS of rats. Klin Wochenschr 1990;68:142-145. http://www.ncbi.nlm.nih.gov/pubmed/2157087

+ Dakshinamurti K, LeBlancq WD, Herchl R, Havlicek V. Nonparallel changes, in brain monoamines of pyridoxine deficient growing rats. Exp Brain Res. 1976;26:355-366. http://www.ncbi.nlm.nih.gov/pubmed/1001386 

Highlights:

• Minimizes jaw clenching, tooth grinding, and muscle cramping.

• Vital for serotonin production.

• Boosts immune system.

• Supports healthy hydration.

Scientific Research Indicates:

Magnesium is needed for more than 300 biochemical reactions in the body including the regulation of the heart beat, blood pressure, and energy metabolism.+ One of magnesium’s major roles is muscle relaxation. Magnesium calms the nerves and relaxes the muscles to minimize jaw clenching and muscle cramping.+  Magnesium Citrate is the highest quality and most absorbable form of Magnesium. Most other supplement companies use the cheaper and lower quality Magnesium Oxide which can diarrhea and nausea.

+ Saris NE, Mervaala E, Karppanen H, Khawaja JA, Lewenstam A. Magnesium: an update on physiological, clinical, and analytical aspects. Clinica Chimica Acta 2000;294:1-26. http://www.ncbi.nlm.nih.gov/pubmed/10727669